Notably, Isshin gave up the Shiba family life and adopted Masaki's family name instead. Ryuken was grateful for the help, but he didn't see Isshin as a dear friend. The two eventually married and started their family, while Ryuken Ishida kept his distance from his acquaintance Isshin for years on end. Masaki was stabilized, and years later after college, she met Isshin again. Kisuke helped Isshin transfer his Soul Reaper powers into Masaki to counteract White's powers, and in so doing, Isshin became an ordinary human - a sacrifice he gladly made. Soon after that, Kisuke Urahara the rogue appeared as well, and he helped Ryuken and Isshin assess Masaki's condition. When Masaki collapsed in the Ishida home, a desperate Ryuken Ishida took her outside, where he encountered Isshin Shiba, who had returned. Masaki was poisoned with White's Hollow essence, and in time, it would kill her.
Masaki gained a positive first impression of Isshin, and they would meet again very soon under even more trying circumstances. At point-blank range, Masaki injured White with her arrow, and White self-destructed while biting her shoulder to infuse its essence into her. Masaki couldn't stand the thought of someone dying because she had failed to help, so she joined the fray with her bow and arrows, luring White into getting closer. Ryuken Ishida's family had ordered Masaki to stay out of harm's way, since they couldn't afford to lose a pureblood like her, but that didn't stop her Masaki from rushing to the scene of battle, where Isshin and White were fighting. RELATED: How Bleach's Kaien Shiba Was Almost Ichigo - Before Ichigo White was strong enough to face a Captain like Isshin, and nearby, a certain adolescent Quincy sensed the battle - Masaki Kurosaki. Isshin had only a passing interest in the world of the living, but he dutifully responded to a distress call from Naruki City, where he encountered a unique Hollow called White, Aizen's own creation. At the time, Isshin was Captain of Squad 10. During the Thousand-Year Blood War arc, Ichigo finally learned the truth of his parents' first meeting, which took place several years before Ichigo was born.